Quality and quantity control at the endoplasmic reticulum
نویسندگان
چکیده
منابع مشابه
Quality and quantity control at the endoplasmic reticulum.
The endoplasmic reticulum (ER) is the site of maturation for secretory and membrane proteins that together make up about one third of the cellular proteome. Cells carefully control the synthetic output of this organelle to regulate both quality and quantity of proteins that emerge. Here, we synthesize current concepts underlying the pathways that mediate protein degradation from the ER and thei...
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ژورنال
عنوان ژورنال: Current Opinion in Cell Biology
سال: 2010
ISSN: 0955-0674
DOI: 10.1016/j.ceb.2010.05.005